Interventions such as Relaxation Response appear to have widespread effects on physiology. Endothelial function, changes in genomic expression, several biomarkers have been associated with chronic stress and cardiovascular dysfunction, and there is some suggestion that elicitation of the Relaxation Response may lead to improvement in-or normalization of-these factors. By studying the impact of the Relaxation Response on endothelial function, genomic expression and biomarkers among subjects with hypertension, it may be possible to better understand the biologic underpinnings of Relaxation Response-type interventions. Furthermore, with a greater understanding of the physiologic mechanisms by which the Relaxation Response works, it may be possible to better target other symptoms and conditions that can be effectively treated by such an intervention.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
58
The Relaxation Response is a type of relaxation. The goal of the Relaxation Response is to consciously elicit a reaction opposite in direction to the stress response.
Relaxation Response is a type of relaxation. This is a technique that elicits a state that is opposite to the stress response.
Massachusetts General Hospital
Boston, Massachusetts, United States
Endothelial Function
Time frame: Eight weeks of Relaxation Response Training
Blood Pressure
Time frame: Eight Weeks of Relaxation Response Training
Genomic Expression
Time frame: Eight Weeks of Relaxation Response Training
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