Study of Individualized Physiotherapy for Airway Clearance in Cystic Fibrosis.

Oslo University Hospital6 enrolled

Overview

The purpose of this study is to investigate individual efficacy in Physiotherapy for Airway Clearance, and to investigate user experience, i.e.utility value and preference.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Cystic Fibrosis

Interventions

PhysiotherapyOTHER

Physiotherapy for Airway Clearance

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis: CF * Age \>18 years * Amount of sputum \>5 ml/60 min * Wet inhalation of saline/DNase/both * Informed consent Exclusion Criteria: * Respiratory failure * Hemoptysis * Bacteriology (burkholderia cephacia, multi-resistent pseudomonas aeruginosa, atypical mycobacteria, MRSA). * Ongoing intravenous medication * Pregnancy

Outcomes

Primary Outcomes

Expectorated sputum (gram)

Total amount of expectorated sputum (g) will be collected and weighed wet after each intervention for eight weeks, using a Mettler TOLEDO Weighing Balance (EL 202, accuracy: 0.01 g). N of 1 trial design. Each trial consist of eight pairs (8 weeks) of treatment periods with two interventions each week (one with Cough Technique and one with Forced Expiration technique), 16 treatments for each participant. Outcome measure after each treatment.

Time frame: 8 weeks

Secondary Outcomes

Patient's experience, i.e. perceived utility value and preference of technique.

Utility value: Measured by self-reported questionnaire after completion of each intervention in week 8. Preference: Measured by three self-reported questions after both interventions in week 8.

Time frame: 8 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.