An Observational Study of Avastin (Bevacizumab) in Patients With Colorectal Cancer

Inclusion Criteria: * Adult patients, age \>/=18 years * Proven metastatic colorectal carcinoma * Patients have measurable disease * Patients are eligible to receive first-line Avastin * Patients have signed data release form Exclusion Criteria: * Contra-indication to receive Avastin according to the local labeling * Participation in a clinical study within 30 days prior to enrolment * Patients have any other primary cancer * Concomitant treatment with other biologics * History of other malignant disease in the past 5 years except basal cell carcinoma