The purpose of this study is to determine whether the use of different dose of LMWH compared with fondaparinux for thromboprophylaxis is efficacious and safety after thoracic surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
362
2.5mg IH qd(8AM) after operation
4100AxaIU IH qd(8AM) after operation
4100AxaIU IH q12h(8Am,8Pm) after operation
Zhongshan Hospital
Shanghai, China
TEG values
1.5ml aterial blood sample will be obtained daily for TEG , and the vulues of TEG,such as R,K,Alpha angle,MA,G,CI ,will be measured
Time frame: three days after surgery
bleeding quantity of chest drainage
all drain from chest tube are gathered and hematocrits are measured to calculate the quantities of bleeding
Time frame: three days after surgery
incidence rate of deep venous thromboembolism(DVT)
incidence of DVT is measured by vascular ultrasonography
Time frame: after surgery up to 7 days
inhospital mortality
the number of death in the period of hospital stay
Time frame: after surgery up to 28 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.