This is a single-center, prospective, randomized, and controlled study to evaluate the effectiveness of OxyBand Dressing for the use as a dressing for autogenous skin donor sites compared to our current standard donor site dressing (Xeroform). Hypothesis is that the mean healing time for wounds treated with the OxyBand dressing will be less than the mean healing time for wounds treated with the Xeroform dressing.
Patients who are scheduled for excision of burns or other injuries will have one of two donor sites covered with the OxyBand Dressing, and the other treated according to standard of care. OxyBand is an FDA (Food and Drug Administration) approved (K043063) wound dressing for delivery of oxygen into the wound. Two small clinical studies using OxyBand have been conducted on standardized laser burn wounds, demonstrating faster healing time compared to a placebo. No studies have compared this dressing to Xeroform dressing, the standard dressing used on donor sites in the USAISR.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Oxygen diffusing dressing applied to study wound
Xeroform control dressing applied to control wound
US Army Institute of Surgical Research, Burn Center
Fort Sam Houston, Texas, United States
Healing Time for Donor Site Wounds
Wounds are inspected on postoperative days 4, 8, and then every two days until the wound is deemed to be healed.
Time frame: number of days to healing
Pain Perceived by Patient
Patient will be asked to rate pain 0-10 (0=no pain, 10=maximum pain) at the study site and the control site. Used Visual Analogue Scale (VAS) for this purpose.
Time frame: Post-Operative Day 4
Patient Will be Asked to Rate Pain 0-10/10 at the Study Site and the Control Site
Time frame: Post-Operative Day 8
Patient Will be Asked to Rate Pain 0-10/10 at the Study Site and the Control Site
Time frame: Post-Operative Day 10
Patient Will be Asked to Rate Pain 0-10/10 at the Study Site and the Control Site
Time frame: Post-Operative Day 12
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