The purpose of this study is to define the current treatment of patients ospitalized with acute cardiogenic pulmonary edema. Clinical and laboratory data collected in the Emergency Department will used to investigate the primary outcome (mortality) and risk factors related to the primary outcome.
ACPE is a common cause of presentation to the Emergency Department (ED). Early recognition of high-risk patients could help in better locating human and technical resources and in deciding adequate treatment and site of care. The investigators planned a real life, multicentric, prospective, web-based observational study performed in Italian Emergency Departments. The investigators enroll consecutive patients admitted to the Emergency Department with acute cardiogenic pulmonary edema, that is defined as all the following: respiratory distress, bilateral rales and congestion on chest X-ray. Demographic, clinical and laboratory findings are collected on admission and during hospitalization to evaluate mortality and risk factors related to mortality.
Study Type
OBSERVATIONAL
Enrollment
1,000
Indications for the use of NIV are at least one of the following: * Respiratory Rate ≥ 30 bpm * PaO2/FiO2 \< 200 * pH \< 7.35 and PaCO2 \> 45 mmH Contraindications for the use of NIV are at least one of the following: * Coma * Hemodynamic instability / shock * Lack of compliance Indications for endotracheal intubation (ETI) are at least one of the following: * Respiratory or cardiac arrest * Coma * Hemodynamic instability
Fondazione IRCCS Ospedale Maggiore Policinico, Mangiagalli e Regina Elena
Milan, Italy, Italy
RECRUITINGmortality
Time frame: Discharge from hospital
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