The hypothesis of the study is to evaluate whether ascorbic acid is able to clear totally implanted central venous catheter
Totally implanted catheter is often occluded and thrombolytic drugs are usually used to restore permeability. In Brazil, the ascorbic acid has been used successfully by a service specialist in cancer treatment. However, no literature on international research that evaluates the efficacy and safety of this procedure. That was why it was decided to develop this research.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
21
comparing three different doses of ascorbic acid: 50 mg, 100 mg and 200 mg administered inside the catheter and maintained for up to 60 minutes
Clinical Hospital of Medicine College of Ribeirão Preto, University of São Paulo
Ribeirão Preto, São Paulo, Brazil
Restore patency
the ascorbic acid is administered and remains inside the catheter within 60 minutes. The recovery of permeability is checked every 15 minutes until the maximum of 60 minutes
Time frame: 60 minutes after administration of ascorbic acid
Eosinophil count
the count of eosinophils was determined by collecting blood sample immediately prior to administration of ascorbic acid and 24 hours after
Time frame: within 24 hours
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