Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis

Meir Medical Center100 enrolled

Overview

Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms. The aim is to examine the effect of a platelet-derived preparation rich in growth factors (PRGFs) in OA of the knee.

Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms. The investigators aim is to examine the effect of a platelet-derived preparation rich in growth factors(PRGFs) in OA of the knee, using parameters of pain, function, quality of life and safety.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

100

Conditions

Osteoarthritis of the Knee

Interventions

Platelet Rich Plasma (Preparation Rich in Growth Factors)BIOLOGICAL

intra articular injection 6ml

Hyaluronic acidDRUG

Intra articular injections: 20 mg / 2 ml

Eligibility

Sex: ALLMin age: 40 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age 40-75 years old * diagnosed Oa of the knee more then 1 year * no knee deformation Exclusion Criteria: * mental of physical disabilities * pregnancy * deformities of the knee

Locations (1)

Meir Medical Center

Kfar Saba, Israel

Outcomes

Primary Outcomes

Improvement in pain, function, quality of life and activity level in knee osteoarthritis

Improvement in pain, function, quality of life, activity level - using scores adapted to measure these parameters in knee osteoarthritis.

Time frame: 1 -2 years

Central Contacts

Lior Laver, MD

CONTACT

+972-50-8464466 laver17@gmail.com

Data from ClinicalTrials.gov

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