The primary purpose of this study is to determine the steady-state plasma pharmacokinetics (PK) and properties of TR-700 into the pulmonary epithelial lining fluid (ELF) and alveolar macrophages (AM) of healthy volunteers.
No applicable.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
20
200 mg, oral, once daily for 3 days.
Trius Investigator Site 001
Hartford, Connecticut, United States
Pharmacokinetic parameters from plasma.
Pharmacokinetic parameters compared with baseline measurements.
Time frame: Day 3
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