Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis

Inclusion Criteria: * Age greater than or equal to 18 years * Onset of severe sepsis within the previous 24 hours * Must be receiving antibiotic therapy * Informed consent form signed by patient or authorized representatives according to local rules or regulations * Able to take liquid medication by mouth or feeding tube Exclusion Criteria: * Receipt of investigational medication within 4 weeks prior to participation in the study * Pregnant or breast-feeding * Severe congestive heart failure * Known severe HIV infection * Presence of severe burns * Patients on high dose immunosuppressants * Patients whose death is considered imminent * Patients whose life expectancy for concurrent illness is less than 6 months * Severe hypoxic encephalopathy or persistent vegetative state * Severe liver disease * Chronically bed bound * Patient, legal representative or patient's primary physician not committed to providing full, aggressive life support