Aim of this study is to measure the effectiveness of topical gentamicin to prevent post-operative infection in inguinal tension-free hernia repair operation.Secondary aim is, if it is effective as a prophylactic agent, to compare it's effect with intra venous single dose cefazolin sodium prophylaxis.
This study is a single blind prospective randomized trial. To measure and compare the effectiveness intra-operative topical gentamicin application in tension-free inguinal hernia repair in contrast to intravenous peri-operative prophylactic cefazolin sodium and combination of gentamicin and cephazolin this study is designed. The patients are grouped randomly in to two groups: * Group1;intravenous cefazolin sodium * Group2;topical gentamicin * Group3:topical gentamicin and intravenous cefazolin sodium As a control group we decided to use the data of control groups ( without any prophylactic agent usage ) of previous studies done in our clinic and medical data base reviews.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
276
80 mg topically, intra-operative,single dose and intravenous 1000 mg cefazolin 1 hour before operation
1000 mg cefazolin application intravenously 1 hour before operation
80 mg gentamicin application intraoperatively
Diskapi Yildirim Beyazit Teaching and research Hospital
Ankara, Turkey (Türkiye)
Rate of Post-operative Infection
Time frame: within the first 30 days after surgery
Number of Infections in Each Study Arm
Patients were examined on postoperative 30 days for the presence of surgical site infection.
Time frame: within the 30 days after surgery
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