Vitamin D Deficiency in Subjects With Chronic Hepatitis C Compared to Healthy Volunteers

Avera McKennan Hospital & University Health Center

Overview

The objective of this study is to assess the prevalence of vitamin D deficiency in patients with chronic Hepatitis C compared to a matched control group of healthy individuals in the Sioux Falls area. It is the hypothesis of this study that vitamin D deficiency is more common in patients with chronic Hepatitis C compared to the healthy control group.

In this study, we will measure vitamin D levels in patients with chronic Hepatitis C and healthy individuals. This study will be important to assess vitamin D inadequacy in patients with chronic Hepatitis C and healthy individuals in this area.

Study Type

OBSERVATIONAL

Conditions

Chronic Hepatitis C

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria for Study Group: * Men and women between the ages of 25 and 55 * Diagnosis of chronic hepatitis C Exclusion Criteria for Study Group: * Taking a vitamin D supplement (by itself or as part of a multivitamin), a calcium supplement and/or biphosphonates * Has acute hepatitis C infection * Has chronic hepatitis B infection * Had gastric bypass surgery * Has chronic kidney disease Inclusion Criteria for Control Group: * Men and women between the ages of 20 and 60 * Has a body mass index (BMI) between 20 and 35 Exclusion Criteria for Study Group: * Taking a vitamin D supplement (by itself or as part of a multivitamin), a calcium supplement and/or biphosphonates * Has any significant illness or medical problem that is not under control or being controlled by medication * History of hepatitis or abnormal liver chemistry tests * History of intravenous drug use

Locations (1)

Avera Research Institute

Sioux Falls, South Dakota, United States

Outcomes

Primary Outcomes

The Vitamin D levels of the 100 subjects will be statistically analyzed as the primary variable and correlated with the rest of the variables via ANOVA and meta-analysis

This research study consists of a single clinic visit. After study subjects have completed the informed consent process and are determined to meet study eligibility, a blood sample will be collected. Values from these lab samples will be compared between study arms.

Time frame: Initial clinic visit

Data from ClinicalTrials.gov

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