Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide

University of Cologne

Overview

Local therapy for glaucoma is known to induce a conjunctival inflammation. Because of this, trabeculectomy is more likely to fail. The investigators exchange the local therapy by systemic therapy using acetazolamide and measure the eye pressure using local therapy and systemic therapy using acetazolamide. The investigators suspect an elevated eye pressure using acetazolamide compared to local therapy. In summary acetazolamide could be a better choice in reference to conjunctival inflammation, but a worse choice in reference to controlling eye pressure.

Study Type

OBSERVATIONAL

Conditions

Control of Elevated Eye Pressure by Local and Systemic Therapy

Interventions

Acetazolamide for glaucoma patients to lower eye pressureDRUG

Acetazolamide tablets 3 times daily for 3 to 4 weeks

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with uncontrolled intraocular eye pressure * Patients with planed trabeculectomy in 3 to 4 weeks Exclusion Criteria: * Patients not meeting the inclusion criteria * Patients with known intolerance to acetazolamide

Locations (1)

University of Cologne

Cologne, Germany

Outcomes

Primary Outcomes

Eye pressure

The eye pressure is measured at the beginning of the study, when the patient is using the maximal tolerated local therapy and 3 to 4 weeks later, when using systemic acetazolamide treatment.

Time frame: Once at the beginning of the study and once 3 to 4 weeks later

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.