Assessment of left ventricular systolic function is the most frequent indication for routine echocardiography. Qualitative eyeball method and biplane modified Simpson's rule, both measuring radial ventricular function, are the currently recommended methods to meet this challenge. Due to the complexity of the myocardial architecture, global left ventricular function also has longitudinal and torsional components. The aim of this study is to evaluate new echocardiographic parameters for longitudinal left ventricular function. A special focus is set on strain imaging by speckle tracking, which is a relatively new technique. Patients with different cardiac pathologies (e. g. dilated cardiomyopathy, coronary artery disease, diastolic dysfunction) will be included and compared to healthy individuals.
Study Type
OBSERVATIONAL
Enrollment
400
University of Heidelberg
Heidelberg, Germany
left ventricular longitudinal systolic strain (LV-LSS) in all patients
left ventricular longitudinal systolic strain (LV-LSS) is measured in all patients by speckle tracking strain imaging
Time frame: 2 years
mitral annular plane systolic excursion (MAPSE) in all patients
MAPSE is measured by M-Mode echocardiography
Time frame: 2 years
mitral annular systolic velocity (MASV) in all patients
MASV is derived from tissue doppler
Time frame: 2 years
diastolic left ventricular function in all patients
Diastolic function is assesed by mitral inflow, mitral annulus velocity, pulmonary vein flow and velocity of flow progression.
Time frame: 2 years
pulmonary artery systolic pressure (PASP) in all patients
PASP is derived from Tricuspid valve regurgitation velocity
Time frame: 2 years
left ventricular ejection fraction (LVEF) in all patients
EF is measured by modified Simpson's rule (biplane)
Time frame: 2 years
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