The investigators assess if repetitive, transcranial alternating current stimulation (rtACS) can improve the speaking quality of the aphasic patient as well as other communication skills as naming, repeating and understanding spoken words, reading and writing. Further, it will be assessed if memory and attentiveness deficiencies after 10 days of therapy with brain stimulation are stabilized and remain stable after a training-free period of 60 days.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
30
Repetitive, transorbital alternating current stimulation (rtACS) is applied with multi-channel device generating weak current pulses in predetermined firing bursts of 2 to 9 pulses. The amplitude of each current pulse is below 1000 microA. Current intensity is individually adjusted according to how well patients perceived phosphenes, i.e. any sensation of flickering light in response to the rtACS stimulation
A clicking sound is presented and the same electrode montage set-up is used during rtASC- and Placebo-stimulation, except that placebo patients received no current (stimulator turned off).
Neurologische Klinik, Medizinische Fakultät der RWTH Aachen, Pauwelsstr. 30
Aachen, Germany
Neurologische Klinik, Brandenburg Klinik Bernau, Brandenburgallee 1
Bernau Waldsiedlung, Germany
Institut für Medizinische Psychologie, Leipziger Str. 44
Magdeburg, Germany
improvement of speaking
assessed by the following tests: * Expressive speaking: ANELT (Amsterdam Nijmegen Everyday Language Test), Aachener Aphasie Test * receptive speaking: ANELT (Amsterdam Nijmegen Everyday Language Test), Aachener Aphasie Test
Time frame: between baseline and 60 days after stimulation
successful stabilization of language
Time frame: 60 days after stimulation
speaking functions 1 - communicative skills
* reading and writing: Aachener Aphasy Test * attentiveness: TAP test battery * working Memory: Wechsler Memory scale-Revised (WMS-R) * emitional state: Vision Analogous Mood Scale (VAMS)
Time frame: baseline to 60 days after stimulation
speaking functions 2 - spontaneous speech faculty
* reading and writing: Aachener Aphasy Test * attentiveness: TAP test battery * working Memory: Wechsler Memory scale-Revised (WMS-R) * emitional state: Vision Analogous Mood Scale (VAMS)
Time frame: baseline to 60 days after stimulation
speaking functions 3 - naming
* reading and writing: Aachener Aphasy Test * attentiveness: TAP test battery * working Memory: Wechsler Memory scale-Revised (WMS-R) * emitional state: Vision Analogous Mood Scale (VAMS)
Time frame: baseline to 60 days after stimulation
speaking functions 4 - repeating
* reading and writing: Aachener Aphasy Test * attentiveness: TAP test battery * working Memory: Wechsler Memory scale-Revised (WMS-R) * emitional state: Vision Analogous Mood Scale (VAMS)
Time frame: baseline to 60 days after stimulation
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speaking functions 5 - understanding
* reading and writing: Aachener Aphasy Test * attentiveness: TAP test battery * working Memory: Wechsler Memory scale-Revised (WMS-R) * emitional state: Vision Analogous Mood Scale (VAMS)
Time frame: baseline to 60 days after stimulation