This study will assess the immunogenicity and reactogenicity of the candidate GSK Biologicals' reduced antigen diphtheria and tetanus toxoids and acellular pertussis- inactivated poliovirus vaccine when administered to healthy subjects aged ≥ 15 years in Germany and ≥ 18 years in France compared to Boostrix™ and inactivated poliovirus vaccine administered separately, and with Revaxis®
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
806
Intramuscular, single
Intramuscular, single dose
Intramuscular, single dose
Intramuscular, single dose
Immunogenicity with respect to components of the study vaccines
Time frame: One month after vaccination (Month 1)
Immunogenicity with respect to components of the study vaccines
Time frame: One month after vaccination (Month 1)
Immunogenicity with respect to some component of the study vaccines
Time frame: At Day 10 after vaccination
Occurrence of solicited local and general symptoms
Time frame: within 15 (Day 0-14) days after vaccination
Occurrence of unsolicited symptoms
Time frame: within 30 days (Day 0-29) after vaccination
Occurrence of serious adverse events
Time frame: Throughout the entire study (from Day 0 to Day 30)
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