Study of the Paclitaxel-Coated Balloon Catheter in Bifurcated Coronary Lesions

Inclusion Criteria: PATIENTS * Patients with stable angina (1-3) or unstable angina (1-3 A-C) or documented silent ischemia * Patients with mental and logistic conditions for the follow-up * Patients should accept an angiographic follow-up at 9 months, a clinical follow-up at 3 years and sign the consent LESIONS * De-novo lesions in the bifurcations of DA/Diag either CX/OM or CD/DP with diameters in the main vessel of 2,5 to 3,8/ 2 to 3,5 and lengths \< 22 mm * The left main lesions in bifurcation are also accepted but with another independent randomization list (specify at randomization) * The diameter of the stenoses should be \>50% in any branch with documented ischemia or more than 70% in absence of an ischemia test * Single vessel or multivessel disease * In case of a PTCA of more than one lesion, the non included lesion should be treated previously to the included lesion Exclusion Criteria: PATIENTS * Patients with STEMI \< 72 hours * Patients with congestive heart failure or NYHA IV, shock or severe valvular heart disease * Patients with short life expectancy, or with problems for platelet antiaggregation * Patients in treatment with hyperthyroidism, in treatment with immunosuppression or anticoagulants, or with alcohol or drug addiction * Patients included in other trials * Patients with a stroke 6 months before * Patients with a surgery one week before * Severe renal failure calculated as GF \< 30 ml/min "Cockcroft Gault" * Women of childbearing age, with probability to become pregnant during the first year of follow-up LESIONS * Evidence of important thrombus within the vessel to treat * Patients with another stent previously implanted at ≤ 15 mm from the current lesion of the study * Lesions affecting bypass * Chronic occlusions to treat * Restenosis in-stent or of a segment in 4 mm close to the target lesion * Severe calcification not totally dilatable with the balloon