The purpose of this study is to determine wether intravenous Phenylephrine, administered as start bolus and following continuous infusion (specific dosage per weight), or optimal lower limb bandaging is more effective in preventing hypotension during caesarean section under spinal anaesthesia in healthy women. The hypothesis is that the Phenylephrine model is superior to lower limb compression in preventing hypotension.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
120
Intravenous infusion Dosage 0,25 microgram/kg bodyweight as bolus, continuous infusion with 0,25 microgram/kg/min
Tight bandaging of lower extremity up to hips with compression bandages
Neither phenylephrine nor lower limb bandaging
Bærum Sykehus
Rud, Akershus, Norway
Invasive arterial bloodpressure
Time frame: Until end of operation, up to roughly 1 hour
pH value from umbilical vessels of the newborn
Time frame: straight after delivery
APGAR score of the newborn
Time frame: 1 + 5 + 10 minutes after delivery
Need for rescue pressor (ephedrine, phenylephrine)
Time frame: Until end of operation, roughly 1 hour
Cardiac Output
Time frame: Until end of operation, roughly 1 hour
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