Prognostic Score To Predict Major Complications After Pancreaticoduodenectomy

Università Vita-Salute San Raffaele700 enrolled

Overview

Pancreaticoduodenectomy (PD) still carries a high rate of severe postoperative complications. No score is currently available to help identify the patient's surgical risk. The purpose of this study was to develop and validate a prognostic score to predict major postoperative complications after PD.

The investigators prospectively collected in an electronic database preoperative, intraoperative and outcome data of 700 patients undergoing PD in our Institution from 2002 to 2010. The investigators used a multivariate logistic regression analysis to create a new score to predict severe complications defined as Clavien-Dindo classification III, IV and V. The score was developed using a random two-thirds of the population (469 patients), and was then validated and calibrated in the remaining third of the patients (231).

Study Type

OBSERVATIONAL

Enrollment

700

Conditions

Pancreatic Neoplasm

Interventions

PancreaticoduodenectomyPROCEDURE

Resection of pancreatic lesion

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Patients undergoing pancreaticoduodenectomy in our Institution Exclusion Criteria: * Metastatic disease * Patient not suitable for surgery

Locations (1)

San Raffaele Hospital

Milan, Italy

Outcomes

Primary Outcomes

Major Complication rate

Clavien-Dindo grade III to V complications considered as major

Time frame: Postoperative. Until 30 days after discharge

Data from ClinicalTrials.gov

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