The purpose of the study is to evaluate the effect of the Modified Atkins Diet in children and adolescents with drug-resistant epilepsy regarding seizure control, and to create a protocol for the use of the Modified Atkins Diet as a treatment for epilepsy in Norway.
The study is a prospective trial on the Modified Atkins Diet for children and adolescents with drug-resistant epilepsy. The Modified Atkins Diet is a less restrictive diet than the classical ketogenic diet, which is usually offered to this group of patients. Twenty patients between 2 and 18 years are included in the study, and the study period is 6 months. The study will be conducted at the National Centre for Child Epilepsy in Norway.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
21
The Modified Atkins Diet; 10 g carbohydrate per day and a high fat intake
The National Centre for Child Epilepsy
Pb. 53, Bærum Postterminal, Norway
Seizure frequency
Seizure frequency is assessed after 1 month, 3 months and 6 months.
Time frame: 6 months
Ambulatory EEG
24-hours EEG before diet treatment and after 6 months on the diet.
Time frame: After 6 months
Body Weight
Body weight was measured before diet treatment, after 1 month, 3 months and 6 months.
Time frame: 6 months
Quality of life
Questionnaire assessing quality of life and life on a strict diet, assessed after one, three and six months.
Time frame: 6 months
Ketosis
Ketosis in blood and urine measured during the whole study period
Time frame: 6 months
Dietary records
3-days dietary records were obtained after two and ten weeks on the diet.
Time frame: 10 weeks
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