Trichuris Suis Ova (TSO) Suspension Versus Placebo in Active Crohn's Disease

Major Inclusion Criteria: * Signed informed consent, * Man or woman between 18 and 75 years of age, * Established diagnosis of Crohn's disease (CD) since at least 3 months prior to screening confirmed by endoscopic and histological, or endoscopic and radiological criteria, * Negative pregnancy test in females of childbearing potential. Major Exclusion Criteria: * Bowel surgery within the last 3 months prior to baseline, * Resection of more than 50 cm of the ileum, * Ileostomy or colostomy, * Septic complications, * Evidence of infectious diarrhoea (i.e., pathogenic bacteria or Clostridium difficile toxin in stool culture), * Abscess, perforation, fistulas, or perianal lesions, * Immediate surgery required (e.g., major stenosis, serious bleeding, peritonitis, ileus), * Clinical signs of stricturing disease, * Parenteral or tube feeding, * Abnormal hepatic function (ALT or ALP \> 2.5 x upper limit of normal \[ULN\] at screening), liver cirrhosis, or portal hypertension, * Abnormal renal function (Cystatin C \> ULN) at screening, * Any severe concomitant cardiovascular, renal, endocrine, or psychiatric disorder, which in the opinion of the investigator might have an influence on the patient's compliance or the interpretation of the results, * Any condition associated with significant immunosuppression, * Active malignancy or treatment with anticancer drugs during the last 5 years. * Existing or intended pregnancy or breast-feeding, * Participation in another clinical trial within the last 30 days, simultaneous participation in another clinical trial, or previous participation in this trial.