A Study of Minirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI).

Inclusion Criteria: * Participants must be documented to have Central Diabetes Insipidus (CDI) by at least two of the following four criteria (a-d): 1. Failure to increase urine osmolality above 300 mOsm/kg during a period of fluid deprivation sufficient to raise plasma osmolality and sodium above the upper limit of normal level for the reference laboratory (usually 295 mOsm/kg and 148 mEq/l, respectively) 2. Complete and continuous control of the DI by desmopressin therapy without "breakthrough" diuresis, hypernatremia, hyponatremia, or symptoms or signs of water intoxication. 3. A deficient plasma vasopressin response to osmotic or non-osmotic stimulation. 4. Absence of the posterior pituitary bright spot on T-1 weighted midsagittal magnetic resonance imaging (MRI) of the brain. * Given written informed consent prior to any trial-related procedure is performed * 24 hour urine volume (mL), urine osmolality (mOsm/kg), urine specific gravity, and serum sodium (mEq/L) maintained at a normal level by desmopressin nasal administration * Outpatient * The participant is, in the investigator's opinion, otherwise healthy * Be willing and able to comply with the protocol requirements including restriction of water intake Exclusion Criteria: * Presence or a history of nephrogenic diabetes insipidus or diabetes mellitus * Presence of uncorrected hypothyroidism, hypoadrenalism or hypogonadism * Abnormalities or disease of the oral cavity that might affect the release and absorption of drug * Unable to be placed on water-intake restriction starting from two hours before bedtime * Presence of a hypothalamus abnormality leading to thirst disorder * Evidence of hepatic, renal, cardiac, or pulmonary dysfunction * Uncontrolled hypertension * Treatment with another investigational product within the past 3 months * Concurrent treatment with diuretics, chlorpropamide, tricyclic antidepressants, indomethacin, carbamazepine * Alcohol dependency or drug abuse * Breastfeeding, pregnant, or likely to become pregnant * A mental condition, the lack of decision-making ability, dementia or a speech handicap * Any other reason that the Investigator believes inappropriate