Phase 1 Study :Safety, Immunogenicity and Dose response of ATH03, a new vaccine against the cholesterol ester transfer protein (CETP), in healthy male subjects with high density lipoprotein cholesterol (HDLc) blood concentrations equal or below 80 mg/dl.
This open-label Phase 1 study will be conducted in three groups of 12 subjects with HDLc blood concentrations equal or below 80 mg/dl at a single study center. 36 subjects will be enrolled.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
36
4 vaccinations
Department for Clinical Pharmacology Medical University Vienna
Vienna, Vienna, Austria
Number of adverse events
Time frame: 264 days
Immunogenicity
Time frame: 264 days
Response to the various applied doses of ATH03
Time frame: 264 days
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