Dialysis is used to control the fluid balance and metabolic state of patients with kidney disease. Control of the metabolic state, via electrolytes, can be monitored using labs that are routinely drawn from patients undergoing continuous hemodialysis. Control of fluid removal is much more difficult. This study aims to determine whether changes in the blood pressure associated with breathing correlate with or predict intolerance to fluid responsiveness with continuous dialysis. We hypothesize that a measurement of changes in blood pressure with breathing called arterial pulse pressure variation may be able to predict the ability to remove fluid during continuous renal replacement therapy.
Study Type
OBSERVATIONAL
Enrollment
7
The University of Chicago Medical Center
Chicago, Illinois, United States
Predictive value of pulse pressure variation for tolerance of fluid removal on CVVHD
Time frame: Iterative 24 hr periods for the duration of CRRT
Increased doses of vasoactive agents on CRRT
Time frame: Iterative 24 hr periods for the duration of CRRT
Inability to meet goal ultrafiltration rate
Time frame: Iterative 24 hr periods for the duration of CRRT
Hypotensive events on CRRT
Time frame: Iterative 24 hr periods for the duration of CRRT
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