GSK2190915 Pediatric Study

Inclusion Criteria: * Male and pre-menarchial female subjects aged 1to \<12 years at screening are eligible for this study. * Investigator diagnosed history of asthma. * Subject weight a minimum of 11kg and above the 10th percentile for their age. * Patients must be controlled on any existing asthma treatment or currently stable off treatment, at screening. * Apart from asthma, eczema and rhinitis, subjects should be healthy and suffer from no other significant medical conditions. * Subjects and parents/guardians must be able to understand and comply with protocol requirements, instructions and protocol-stated restrictions. Parents/guardians must have the ability to read and write. A signed and dated informed consent from at least one parent/guardian, and, for subjects ≥ 7 years old an accompanying informed assent from the subject prior to admission to the study. \- AST and ALT \< 2xULN. Exclusion Criteria: * Subjects who have changed their asthma medication, dose or regime within 4 weeks of screening * Administration of anti -leukotriene therapies for 14 days before screening and during the study. * Any medical condition or circumstance making the volunteer unsuitable for participation in the study. * Any clinically relevant abnormality identified on the screening medical assessment. * Culture-documented or suspected bacterial or viral infection of the upper or lower respiratory tract, sinus or middle ear that is not resolved within 4 weeks of screening and led to a change in asthma management. * Administration of any vaccinations within 2 weeks of screening or during the study * Parent/guardian has history of psychiatric disease, intellectual deficiency, substance abuse, or other condition which will limit the validity of consent to participate in this study. * Any adverse reaction including immediate or delayed hypersensitivity to any component of study drug * A subject will not be eligible for this study if he/she is an immediate family member of the participating Investigator, sub-Investigator, study coordinator, or employee of the participating Investigator. * Children who are wards of the state or government. * The subject has a screening QTc value of \>450msec, PR interval outside the range 120 to 220msec or an ECG that is not suitable for QT measurements.