Study to Assess Safety, Tolerability, and Pharmacokinetics of Oral Doses for AC430 in Healthy Subjects

Important Inclusion Criteria: 1. Healthy normal males and females, age 18 to 45, inclusive, at the time of consent 2. Able to communicate effectively in the English language 3. Able to provide valid, written informed consent 4. Able to swallow up to 20 capsules of study drug 5. BMI (body mass index) ranging between 18 and 30 kg/m2, inclusive 6. Minimum weight of 50 kg 7. Serum Creatinine ≤ ULN (upper limit of normal) and estimated creatinine clearance at screening of ≥ 80 mL/min per the Cockcroft-Gault equation 8. Total serum bilirubin ≤ ULN (may be repeated to confirm eligibility) 9. Serum aspartate transaminase (AST) and alanine transaminase (ALT) ≤ ULN (may be repeated to confirm eligibility) 10. Male subjects must either be sterile or agree to use from Check-in until 90 days following the last dose of AC430, an acceptable form of birth control. 11. Female participants must be either of non-child-bearing potential or agree to use an acceptable form of birth control. Important Exclusion Criteria: 1. History of clinically significant drug allergy 2. Participation in another clinical trial with receipt of an Investigational Product within 90 days before dose administration (or 5 half-lives, whichever is longer) 3. Major surgery within 90 days before study enrollment 4. Use of prescription, over the counter, or herbal medications or supplements, including oral contraceptives within 14 days of check-in 5. A history of drug abuse or a history of alcohol abuse within 1 year prior to Screening 6. Current or recent (within 30 days before enrollment) use of tobacco or nicotine products 7. Consumption of alcohol containing beverages \> an average of 14 drinks per week or unwillingness to refrain from ethanol consumption while confined to the study unit 8. Inadequate venous access that would interfere with obtaining blood samples 9. Recipients of blood transfusion or transfusion of blood or plasma products, within 90 days before study drug administration 10. Donation of blood ≥ 500 mL within 2 months before study drug administration 11. History or positive laboratory evidence of Human immunodeficiency virus (HIV), Hepatitis B antigen and antibody, or Hepatitis C, or history of Tuberculosis (TB) infection, or a positive result for Quantiferon Gold test 12. Prolonged average of the corrected QTc by Fridericia's correction factor (QTcF) interval on screening electrocardiogram (ECG) triplicate (≥ 450 ms for males and ≥ 470 ms for females) 13. Abnormal laboratory values that are considered clinically significant by the Investigator 14. History of cancer 15. History of eating disorders within the past 3 months 16. History of a seizure disorder or clinically significant head injury 17. Positive urine drug screen for drugs of abuse including alcohol 18. Active infection within 90 days of check-in 19. Medical condition, serious intercurrent illness, cardiovascular, pulmonary, neurologic, psychiatric, renal, hepatic or gastrointestinal disease, or other extenuating circumstance that, in the judgment of the Principal Investigator, could jeopardize subject safety or interfere with the objectives of the study