Hypothesis: Subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, preventing or retarding the progression of recurrence.
1. Impending recurrent pterygium 2. Anti-VEGF therapy * Bevacizumab * Subconjunctival injection * Suppress neovascularization
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
80
topical 0.1% fluorometholone eye drops 4 times daily for 4 weeks
subconjunctival bevacizumab 1.25 mg/0.05mL
subconjunctival bevacizumab 2.5 mg/0.1mL
Ramathibodi Hospital
Bangkok, Bangkok, Thailand
Severity of impending recurrent pterygium
Time frame: 3 months
Visual analog scales
Time frame: 3 months
Adverse reactions
Time frame: 3 months
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subconjunctival bevacizumab 3.75 mg/0.15mL