Prospective Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine

Inclusion Criteria: 1. 18-70 years old, male or female 2. Primary treatment of phase I-IVA head and neck cancer patients, identified by histological and pathological diagnosis 3. Postoperative patients should receive radiation treatment in 12 weeks 4. ECOG \<2 5. Expected lifetime ≥6months 6. No severe complications (hypertension, CHD, diabetes and psychiatric history, etc.) 7. Not involved in other clinical trials 8. Sign ICF Exclusion Criteria: 1. ECOG \>2 2. Suffered other cancers in the past 5 years 3. Received amifostine treatment in the past 4 weeks 4. Unable to complete treatment or sign ICF because of medical or physical reasons