Electronic Intervention for HIV Medication Adherence

Oklahoma State University Center for Health Sciences97 enrolled

Overview

The purpose of this study is to develop and examine the feasibility and initial efficacy of a computer-based intervention to improve medication adherence among people living with HIV.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

HIV

Interventions

Life Steps for Medication AdherenceBEHAVIORAL

The intervention was adapted into an electronic version of the empirically supported Life Steps intervention for HIV medication adherence. Education about HIV and medication adherence, motivational interviewing, cognitive behavioral techniques, and problem-solving strategies to improve medication adherence and clinical outcomes in people living with HIV were also included in the intervention.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * infected with HIV * over age 18 * currently prescribed a Highly Active Antiretroviral Therapy (HAART) regimen * prescribed a regimen for the first time, changing regimens, or report adherence below 95% agree to brief follow-up interviews Exclusion Criteria: * physical impairment that would prevent them from successfully completing the computer-based program (e.g., blind, deaf, severe neuropsychological impairment) * Actively psychotic * Not fluent in English

Locations (1)

Internal Medicine Specialty Services

Tulsa, Oklahoma, United States

Outcomes

Primary Outcomes

HIV medication adherence

Self-reported adherence to HIV medications will be assessed using the AACTG Medication Adherence Questionnaire (M. A. Chesney, et al., 2000).

Time frame: up to 6 months

Secondary Outcomes

HIV Treatment Adherence Self-Efficacy

Self-efficacy for adherence to HIV medications will be assessed using the HIV-ASES (Johnson et al., 2007). The HIV-ASES is a 12-item scale of patient confidence in their ability to carry out behaviors related to adhering to medication regimens. Responses range from 1 ("cannot do it at all") to 10 ("completely certain can do it"). Item scores are averaged with higher scores indicating higher adherence self-efficacy.

Time frame: Baseline, 1-month, 3 months, and 6-months

Quality of Life

Quality of life will be assessed using the McGill Quality of Life questionnaire (S. Robin Cohen, Hassan, Lapointe, \& Mount, 1996). This instrument is a 16-item scale that assesses quality of life in four domains: physical well-being, psychological well-being, existential well-being, and support; each item is assessed on a 0-10 point scale.

Time frame: Baseline, 1-month, 3-months, and 6-months

Viral Load

Time frame: Baseline, 1 month, 3 months, and 6 months

CD4 cell count

Time frame: Baseline, 1 month, 3 months, and 6 months

Data from ClinicalTrials.gov

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