Patients with mild to moderate traumatic brain injury (TBI) are at risk for secondary neurological deterioration. Their outcome within the first week after injury could be predicted by clinical signs, brain CT scan and transcranial doppler (TCD) on admission to the emergency room. The investigators aim to evaluate the diagnostic performance of TCD to screen patients presented with mild to moderate TBI and mild lesions on CT scan, i.e., Trauma Coma Data Bank, TCDB classification II. The principal outcome measure is the negative predictive value of TCD.
Study Type
OBSERVATIONAL
Enrollment
369
Negative predictive value of transcranial doppler in patients with mild to moderate traumatic brain injury
CHRA Annecy
Annecy, Auvergne-Rhône-Alpes, France
CHU Grenoble
Grenoble, Isere, France
Ch Belley
Negative predictive value of transcranial doppler
Patient with mild to moderate traumatic brain injury (Glasgow Coma Scale 9-15) and a CT scan (TCDB II).TCD is performed within 8 hours after the trauma. Aggravation defined by: * a decrease in the Glasgow Coma Scale of 2 points or more from the initial value, in the absence of pharmacological sedation. * a neurological deterioration sufficient to warrant intervention: mechanical ventilation, sedation, osmotherapy, barbiturates, transfer to more intensive care, or neurosurgical intervention.
Time frame: within the first week after the injury
the impact of transcranial doppler for initial patient management
Number of brain CTscan performed within 7 days after the trauma. Number of devices inserted to monitor intracranial pressure. Secondary admissions to intensive care unit. Length of hospital stay.
Time frame: within the first week after trauma
Secondary neurological aggravation: risk factors and consequences.
Neurological outcome on day 7 and day 28 after trauma, as measured with disability rating scale. Number and type of interventions for neurological deterioration
Time frame: neurological outcome on D7 and D28
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Belley, France
CHU
Besançon, France
Ch Briancon
Briançon, France
Ch Cannes
Cannes, France
Ch Chambery
Chambéry, France
CHU
Clermont-Ferrand, France
CHU
Dijon, France
Ch Grasse
Grasse, France
...and 11 more locations