A 12 Week Study to Assess Changes in Joint Inflammation Using Ultrasonography in Patients With Rheumatoid Arthritis (RA)

Inclusion Criteria: * Diagnosed with adult-onset Rheumatoid Arthritis (RA) \>6 months and \<3 years * Active RA * Must have failed at least one disease modifying Anti Rheumatic Drug (DMARD) treatment * Subject can have attempted no more than one previous Anti Tumor Necrosis factor (anti-TNF) and discontinued due to drug intolerance Exclusion Criteria: * Subject cannot have a second non-inflammatory musculoskeletal condition * Subject cannot have a diagnosis of any other inflammatory arthritis * Subject cannot have any previously infected prosthesis * Subject cannot have arthroplasties in any of the joints assessed in the study * Subject cannot have a history of chronic infections * Subject cannot have known Tuberculosis (TB) disease, high risk of acquiring TB, or latent TB infection * Subject cannot have a history of or current Lymphoproliferative disorder * Subject cannot have known Human Immunodeficiency Virus (HIV) infection * Subject cannot have received a live or attenuated vaccine within 8 weeks * Subject cannot have current or history of malignancy * Subject cannot have a history of blood disorders * Subject cannot have a current or recent history of severe, progressive, and/or uncontrolled renal, hepatic, hematological, gastrointestinal, endocrine, pulmonary, cardiac, neurological or cerebral disease * Subjects must not have a history of adverse reaction to Polyethylene glycol (PEG), a protein medicinal product, or ultrasound gel applied to the skin