Effect of Dietary Fat on Glycemic Control in Type 1 Diabetes

Joslin Diabetes Center10 enrolled

Overview

The purpose of this study is to determine if dietary fat alters insulin requirements in type 1 diabetes.

This cross-over prospective study will require a two day admission to the clinical research center. Subjects will undergo closed loop glucose control and will received a diet with controlled macronutrient content.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Type 1 Diabetes

Interventions

High fat mealOTHER

40 grams saturated fat

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * type 1 diabetes using insulin pump and CGM Exclusion Criteria: * renal or hepatic failure * cancer or lymphoma * malabsorption or malnourishment * hypercortisolism * alcoholism or drug abuse * anemia (hematocrit \< 36 in females and \<40 in males) * eating disorder * dietary restrictions * Acetaminophen allergy * Chronic acetaminophen use * Glucocorticoid therapy

Locations (1)

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Outcomes

Primary Outcomes

Change in insulin requirements

Time frame: postprandially until 8 hours

Data from ClinicalTrials.gov

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