Both Kidney transplantation (KT) and Chronic Kidney Disease (CKD) patients have reduced kidney function. Low serum magnesium is more prevalent in KT recipients. The present study examines the difference in vascular calcification between KT and CKD and its association with serum magnesium.
Kidney transplantation (KT) improved quality of life and longevity of CKD patients. Nevertheless, kidney function deteriorates overtime in a manner not different from CKD counterparts. Hypomagnesemia is prevalent in KT recipients secondary to immunosuppressive therapy. In addition to serum calcium, phosphate and elemental calcium intake, the relationship between low serum magnesium and vascular calcification (VC) has been observed in small studies in CKD. Whether low serum magnesium associates with VC in KT has never been elucidated. The present study compares vascular calcification between KT and CKD and its association with serum magnesium.
Study Type
OBSERVATIONAL
Enrollment
400
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Phayathai, Bangkok, Thailand
The difference in vascular calcification score between KT and CKD
Time frame: Baseline
The association of serum magnesium with vascular calcification in KT
Time frame: Baseline
The association of serum magnesium with vascular calcification in CKD
Time frame: Baseline
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