Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?

Copenhagen University Hospital at Herlev3 enrolled

Overview

The purpose of this study is to determine if the pre-operative levels of sex-hormones can be used to identify the varicocele patients who can expect improvements in their semen parameters following varicocelectomy.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Varicocele Infertility Semen Quality

Interventions

Hormone and semen measurements before varicocelectomyPROCEDURE

Before surgery we will measure sex-hormone levels and semen parameters. This will be repeated after the varicocelectomy to record any changes.

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Varicocele (grade 1-3) and surgery planned for this condition * At least 18 years of age Exclusion Criteria: * Fever within 3 months before the first semen sample * Malformations of the uro-genital tract * Karyotype other than 46, XY or Y micro deletions * Endocrine disease * Chronic disease * Medications which reduce semen quality * Epididymitis within 6 months before surgery

Locations (2)

University Department of Growth and Reproduction GR, Section 5064, Rigshospitalet

Copenhagen, Denmark

Department of Urology, Herlev Hospital

Herlev, Denmark

Outcomes

Primary Outcomes

Change in semen parameters

Time frame: February 2017 (anticipated duration of the study)

Secondary Outcomes

Change in hormone levels

Time frame: February 2017 (anticipated end of the study)

Data from ClinicalTrials.gov

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