The study was conducted to investigate the effect of vitamin d3 alone and in combination with calcium phosphate on bone metabolism and further physiological parameters in healthy subjects. It is postulated that calcium phosphate beneficially influences the bone specific action of vitamin d3.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
60
20 subjects consume for 8 weeks a bread enriched with calcium phosphate \[1g calcium/d\]
20 subjects consume for 8 weeks a bread with vitamin d3 \[10µg/d\]
20 subjects consume for 8 weeks a bread enriched with calcium phosphate \[1g calcium/d\] and vitamin d3 (10µg/d\]
Friedrich-Schiller-University Jena, Institute of Nutrition, Department of Nutritional Physiology
Jena, Thuringia, Germany
bone resorption and bone formation markers in blood and urine
Time frame: 8 weeks
concentration of minerals in blood, stool and urine
Time frame: 8 weeks
blood lipids
Time frame: 8 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
All participants consume two weeks before intervention a bread without calcium an vitamin d.