To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" (≥95% re-epithelialization) of a partial thickness target thermal burn.
This phase 2 pilot study will assess the safety and efficacy of topical MW-III on thermal burns.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Topical application, twice a day
Topical application, twice a day
Valleywise Health Medical Center
Phoenix, Arizona, United States
RECRUITINGUniversity of CA Davis Medical Center
Sacramento, California, United States
RECRUITINGMedStar Washington Hospital Center
Washington D.C., District of Columbia, United States
Time to healing (≥95% re-epithelialization) of the partial thickness target burn.
Time to healing (≥95% re-epithelialization) of the partial thickness target burn.
Time frame: 28 days Treatment Period
Proportion of subjects with partial thickness burns that are healed at each scheduled study assessment.
Proportion of subjects with partial thickness burns that are healed at each scheduled study assessment.
Time frame: 28 days Treatment Period
Proportion of subjects with partial thickness burns determined by PI to require skin grafting of burn wound by Day 28.
Proportion of subjects with partial thickness burns determined by PI to require skin grafting of burn wound by Day 28.
Time frame: 28 days Treatment Period
Scar scores (POSAS) of the partial thickness target burn and all other partial thickness burns at Day 28.
Scar scores (POSAS) of the partial thickness target burn and all other partial thickness burns at Day 28.
Time frame: 28 days Treatment Period
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University of Iowa Health Care
Iowa City, Iowa, United States
RECRUITINGProactive CR Mexico SA de CV
Irapuato, Mexico
RECRUITINGSMIQ S de R. L de CV
Querétaro City, Mexico
RECRUITING