A Double Blinded Study to Examine the Effect of Coated Suppositories on Fecal Incontinence in Patients With Spinal Cord Injury

Inclusion Criteria: Signed written informed consent; Male or female subjects 18 to 55 years of age; Spinal cord lesion/disease/injury at any level at least 3 months from injury. FISI (Fecal Incontinence Severity Index) \> 8 units. The patient is able to understand the treatment and is willing to comply with the prescribed regimen Exclusion Criteria: * Known allergy to experimental drug.. * Porphiria. * Glaucoma. * Pregnancy or lactation. * Active or past history of cardiovascular or cerebrovascular disease including unstable angina, myocardial infarction, transient ischemic attacks/stroke, clinically significant arrhythmia, congestive heart failure, or cardiac valve abnormalities; * Type 1 diabetes mellitus; * Insulin treated type 2 diabetes mellitus. * Renal insufficiency. * Liver insufficiency. * Malignant disease within 5 years of screening; * Has hypertension (sitting blood pressure \> 140/90 mmHg at screening) * History of rectal surgery. * History of HIV, hepatitis B, hepatitis. * Has used, in the last four weeks, drugs that may affect blood coagulation, such as Aspirin (at a dose above 250 mg/day), Warfarin, Sintrom, Enoxaparin, Nadroparin, Heparin, Clopidogrel, Ticlopidine. * Use of tricyclic or monoamine-oxidase inhibors. * Has upon physical examination a rectal deformation or signs of rectal disease such as fissure, bleeding hemorrhoids, fistula, infection or space occupying lesion. * Unable to understand the use instruction for the coated suppository, as judged by the investigator.