The purpose of this study is to investigate the incidence of reflux in patients with spinal cord injury in relation to the lesion level, duration of injury and bladder management
Vesico-ureteral reflux was the main cause for renal failure and reduced life expectancy in patients with neurogenic bladder dysfunction due to spinal cord injury. Neurogenic detrusor overactivity leads to high intravesical pressure and may induce reflux. Decreasing intravesical pressure and increasing bladder capacity is necessary to prevent reflux and secondary renal failure.
Study Type
OBSERVATIONAL
Enrollment
120
Assessment of bladder function during video urodynamic determine of incidence degree and localization of vesico ureteral reflux based on the result of video urodynamics
Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital
Zurich, Canton of Zurich, Switzerland
Incidence and degree of vesico ureter renal reflux
video urodynamic, ultrasound examination
Time frame: average: yearly scheduled control
pdet (cmH2O)
urodynamic parameter, detrusor pressure
Time frame: average: yearly scheduled control
Medication
name of drugs and applied dosis
Time frame: average: yearly scheduled examination
possible complications
urinary tract infection, pyelonephritis, renal dysfunction
Time frame: average: yearly scheduled examination
maximum cystometric capacity
the volume at which a patient, with normal sensation, fells he/she can no longer delay micturition
Time frame: average: yearly scheduled control
compliance mL/cmH2O
Compliance is the change in volume divided by change in detrusor pressure expressed as mL/cmH2O.
Time frame: average: yearly scheduled control
bladder management
most common: intermittent catheterisation, indwelling catheter, external condom urinal for male patients
Time frame: average: yearly scheduled control
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