The purpose of this study is to assess blood levels of Ceftaroline fosamil in children.
To characterize single dose pharmacokinetics of Ceftaroline fosamil in children.
Study Type
INTERVENTIONAL
Allocation
NA
Masking
NONE
Enrollment
53
Single dose of 15 mg/kg (up to 600 mg) by intravenous infusion
Investigational Site
Phoenix, Arizona, United States
Investigational Site
Little Rock, Arkansas, United States
Investigational Site
Orange, California, United States
Pharmacokinetic profile of Ceftaroline fosamil, plasma concentrations time profile of ceftaroline fosamil by patient, age cohort and dosage level, and Safety and tolerability of ceftaroline fosamil following a single dose of ceftaroline.
This study has 3 primary outcome measures: plasma concentration of ceftaroline fosamil and its metabolites from blood samples after a single dose; PK profile of ceftaroline, and safety, where number of subjects with serious and non-serious adverse events and type of frequency of adverse events will be reported.
Time frame: Up to 5 days
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Investigational Site
San Diego, California, United States
Investigational Site
Indianapolis, Indiana, United States
Investigational Site
Louisville, Kentucky, United States
Investigational Site
Shreveport, Louisiana, United States
Investigational Site
Jackson, Mississippi, United States
Investigational Site
Omaha, Nebraska, United States
Investigational Site
Akron, Ohio, United States
...and 5 more locations