Comparison of Surgical Time and Efficiency of Total Knee Arthroplasty

Inclusion Criteria: * Subject is male or female and between the ages of 18 and 80 years old, inclusive. * Subject requires a primary total knee replacement and is considered by the Investigator to be suitable for the specific knee prosthesis identified in the protocol. * Subject has given voluntary, written informed consent to participate in this clinical investigation and has authorized the transfer of his/her information to DePuy * Subject, in the opinion of the Clinical Investigator, is able to understand this clinical investigation, and co-operate with investigational procedures. * Subject, who, in the opinion of the Clinical Investigator, are suitable for implantation using TruMatch™ instrumentation. For example, no femoral nails/bone plates that extend into the knee, ie. within 8cm of joint line; no metal device that could cause CT scatter about the knee and no deformities greater than 15 degrees of fixed varus, valgus, or flexion contracture are consistent with TruMatch™ instrumentation. Exclusion Criteria: * The Subject is a woman who is pregnant or lactating. * The Subject has participated in a clinical investigation with an investigational product in the last 3 months. * The Subject is currently involved in any personal injury litigation, medical-legal or worker's compensations claims. * The Subject has previously had a prosthetic knee replacement device (any type) of the affected knee. * The Subject requires simultaneous bilateral total knee replacements. * The Subject had a contralateral TKA and that knee was previously entered in the study. * Subject in whom the surgeon intends to implant a knee prosthesis that is not in the PFC Sigma primary knee system. * Subject who has inflammatory arthritis. * Subject who has a Body Mass Index (BMI) of ≥ 40. (Please see Table 2-1: Definition of Terms, for BMI definition and calculation formulas).