A study to investigate if the pharmacokinetics of ASP1941 is different in Type 2 Diabetes Mellitus (T2DM) patients with different grades of renal failure compared with T2DM patients with normal renal function and healthy volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
40
Oral
Unnamed facility
Brno, Czechia
Unnamed facility
Prague, Czechia
Unnamed facility
Balatonfüred, Hungary
Unnamed facility
Warsaw, Poland
Unnamed facility
Bratislava, Slovakia
Effect of grade of renal impairment on the pharmacokinetics of ASP1941
Time frame: 5 days
Effect of grade of renal impairment on the pharmacodynamics of ASP1941
Time frame: 5 days
Assessment of safety through evaluation of adverse events, physical examination, vital sins, lab-tests and 12-lead ECG
Time frame: 5 days
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