Pulsed Dye Laser for the Psoriatic Nail

Taipei Medical University WanFang Hospital25 enrolled

Overview

The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.

Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Psoriatic Nail

Eligibility

Sex: ALLMin age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Psoriatic nail refractory to other topical and systemic treatment therapy * ≧ 16 years old Exclusion Criteria: * Patient with pregnancy * Patient with photo sensitivity * Patient with severe wound around finger nails or paronychia * Patient with hypersensitivity to Tazarotene cream

Locations (1)

Taipei Medical University - WanFang Hospital

Taipei, Taiwan

Outcomes

Primary Outcomes

NAPSI

Time frame: 3rd and 6th months

global physician assessment

Time frame: 3rd and 6th months

Data from ClinicalTrials.gov

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