Safety and Efficacy Study of Antiviral Local Application to Treat High Grade Cervical Intraepithelial Lesions (CIN2/3)

Inclusion Criteria: * Women aged between 18 and 50 years old * Informed consent signed * Cervical lesion classified CIN 2 or 3, on a biopsy made during the 60 days before inclusion * No sexual activity, or proved sterility, or use of effective mechanical, hormonal or intrauterine contraception during 30 days following inclusion (except vaginal ring Nuvaring, diaphragm and spermicide) Exclusion Criteria: * Invasive or microinvasive cervical neoplasia * Pregnancy or breast feeding * Subtotal hysterectomy * Current renal impairment * Current immune disorder including serology HIV + * Current use of drugs interfering with renal function * Current use of oncologic treatment * Current use of immune treatment * Current use of anti-viral treatment * Current vaginal application of drugs or cosmetics * Prior treatment with the antiviral on the cervix * Local or general condition incompatible with the experimental treatment in the opinion of the principal investigator * Current or recent participation to another experimental study during the last 3 months before the screening visit