Emerging research suggests fiber, particularly digestion-resistant maltodextrins such as Fibersol-2, may impact satiety, by decreasing hunger, prolonging satiation, and/or increasing satiety signals from the gut. This research aims to determine whether or not Fibersol-2 may impact satiety, by decreasing hunger, prolonging satiation, and/or increasing satiety signals from the gut.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
20
Nutrition and Wellness Research Center
Ames, Iowa, United States
Visual analog scale questionnaire subjective satiety responses
Hunger survey (30 minutes before meal and every half hour for 4 hours postprandial) (analogue scores)
Time frame: 4 hours
serum cholecystokinin (CCK)
0, 30, 60, 120, 180, and 240 min post-meal
Time frame: 4 hours
serum peptide YY (PYY)
0, 30, 60, 120, 180, and 240 min post-meal
Time frame: 4 hours
serum glucagon-like peptide-1 (GLP-1)
0, 30, 60, 120, 180, and 240 min post-meal
Time frame: 4 hours
serum ghrelin
0, 30, 60, 120, 180, and 240 min post-meal
Time frame: 4 hours
serum gastric inhibitory peptide (GIP)
0, 30, 60, 120, 180, and 240 min post-meal
Time frame: 4 hours
serum total cholesterol
0, 30, 60, 120, 180, 240 min
Time frame: 4 hours
serum LDL-cholesterol
0, 30, 60, 120, 180, 240 min
Time frame: 4 hours
serum HDL-cholesterol
0, 30, 60, 120, 180, 240 min
Time frame: 4 hours
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serum triglycerides
0, 30, 60, 120, 180, 240 min
Time frame: 4 hours
serum free fatty acids
0, 30, 60, 120, 180, 240 min
Time frame: 4 hours
serum glucose
0, 30, 60, 90, 120 min
Time frame: 2 hours
serum insulin
0, 30, 60, 90, 120 min
Time frame: 2 hours
gastrointestinal symptoms questionnaire
subjects recorded incidents and severity of gastrointestinal symptoms post treatment over 24 h
Time frame: 24 h