Effects of Heating Massaging Vibrating Vicinity of the Insulin Delivery Site

Hadassah Medical Organization100 enrolled

Overview

The aim of this experiment is to test the pharmacodynamics and pharmacokinetics of insulin analogs and their dependence on external and physiological alterations. The investigators plan compare the pharmacodynamics of insulin analog delivery in regular conditions and in the presence of increased perfusion of the delivery site, achieved by way of local warming, movement and topical application of Capsaicin cream. The investigators will also test the effect of local heating and topical application of Capsaicin cream on the post prandial glucose levels following a bolus.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

DIABETES

Eligibility

Sex: MALEMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Participant age between 18- 65 years old 2. Type I or Type II diabetes 3. HbA1c 6-12% 4. Does not suffer from sever hypertension, kidney, liver or heart disease 5. Does not suffer from active Ischemic heart disease 6. Is willing to sign the consent form Exclusion Criteria: 1. Participants age \< 18 or \> 65 2. Pregnancy 3. Breast feeding women 4. Un-controlled diabetes, HbA1c values \> 12% range 5. Suffers from active Ischemic heart disease 6. Alcohol addiction 7. Is not prepared to signed the informed consent

Locations (1)

Hadassah Medical Organization,

Jerusalem, Israel

Central Contacts

Itamar Raz, MD

CONTACT

00-972-2-6778021 ntv502@netvision.co.il

Arik Tzukert, DMD

CONTACT

00 972 2 6776095 arik@hadassah.org.il

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.