Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia?

Shahid Beheshti University of Medical Sciences185 enrolled

Overview

Purpose: : This study was performed to compare the accuracy of non-cycloplegic photorefraction with cycloplegic refraction in detection of refractive amblyopia risk factors and determine some corresponding beneficial cut points. Method: In this diagnostic accuracy study, right eyes of 185 children (1 to 14 years) underwent first non-cycloplegic photorefraction (with PlusOptix SO4 photoscreener) and then cycloplegic refraction from October 2009 to August 2010. Based on the cycloplegic refraction results, hyperopia (≥+3.5D), myopia (≥-3D), astigmatism (≥1.5D), and anisometropia (≥1.5D) were set as criteria based on AAPOS guidelines. The difference in detection of refractive amblyopia risk factors between the two methods was the main outcome measure.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

DOUBLE

Enrollment

185

Conditions

Amblyopia

Interventions

photorefraction is a name of device.

Eligibility

Sex: ALLMin age: 1 YearMax age: 14 Years

Medical Language ↔ Plain English

Inclusion Criteria: * \> 1 year old /with consent Exclusion Criteria: * mental retardation * impaired fixation * strabismus * ptosis and any other organic ophthalmic disorder interfering with refraction

Locations (1)

Labbafinejad medical center

Tehran, Iran

Outcomes

Primary Outcomes

refraction

cycloplegic auto refraction \& Non-cycloplegic photorefraction

Time frame: 10 months

Secondary Outcomes

hyperopia (≥+3.5D), myopia (≥-3D), astigmatism (≥1.5D), and anisometropia (≥1.5D) were set as criteria based on AAPOS guidelines.

cycloplegic auto refraction \& Non-cycloplegic photorefraction

Time frame: 10 months

Data from ClinicalTrials.gov

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