This randomized clinical trial studies minimally invasive surgery in treating patients with spinal tumors. Posterior spinal tumor resection and anterior and posterior spinal tumor resection are less invasive types of surgery for spinal tumors and may have fewer side effects and improve recovery
PRIMARY OBJECTIVES: I. Length of operation (operating room \[OR\] time). II. Estimated blood loss (EBL). III. Complication rate. IV. Neurological preservation. SECONDARY OBJECTIVES: I. Motor strength and sensory level (neurological outcome). II. Bladder and bowel function. III. Post-operative pain. IV. Hospital length of stay (recovery time). V. Arthrodesis. OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I: Patients undergo posterior spinal tumor resection on day 0. ARM II: Patients undergo anterior and posterior spinal tumor resection on day 0. After completion of study treatment, patients are followed up for 6 months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
7
Undergo posterior spinal tumor resection
Undergo anterior and posterior spinal tumor resection
Ancillary studies
City of Hope Medical Center
Duarte, California, United States
Estimated blood loss (EBL); in milliliters (ml)
Will be comparing means with the Wilcoxon test.
Time frame: Day 0
Length of operation (OR time)
Will be comparing means with the Wilcoxon test.
Time frame: Day 0
Complication rate
Time frame: Day 0
Neurological preservation
Time frame: Post operation day 90
Length of stay
Time frame: Less than 7 days
Pain symptoms
Time frame: Pre-operation, post-op day 3, discharge, post-op days 7, 28, 60, and 90
Assessment of neurologic function using the ASIA (American Spinal Injury Association) Impairment Scale
This is an assessment of sensory and motor functions based upon the ASIA Impairment Scale
Time frame: Pre-operation, post-op day 3, discharge, post-op days 7, 28, 60, and 90
Evaluation of arthrodesis
Plain x-ray films and CT scans are used to determine the success of arthrodesis (spinal fusion in this case) which is the artificial induction of joint ossification between two bones via surgery. This is done to relieve intractable pain in a joint which cannot be managed by pain medication.
Time frame: Post-op day 1, 28, and 90
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