The prevalence of vitamin D deficiency increases as kidney function declines. As a result, many hemodialysis patients often have low levels of vitamin D. Recent evidence has shown that vitamin D supplementation may improve many aspects of poor health such as heart disease and inflammatory markers. The objectives of this study are to determine how supplementing dialysis patients with ergocalciferol increases vitamin D levels, how long vitamin D levels can be maintained after a 6 month treatment course, and to examine the effect of ergocalciferol on biomarkers of inflammation and vascular health.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
20
Ergocalciferol capsules 50,000 IU once weekly for 6 months
Placebo by mouth once weekly for 6 months
Stratton VA Medical Center
Albany, New York, United States
Hortense and Louis Rubin Dialysis Center
Clifton Park, New York, United States
Hortense and Louis Rubin Dialysis Center
Saratoga Springs, New York, United States
Hortense and Louis Rubin Dialysis Center
Troy, New York, United States
The sustainability of 25-hydroxy-vitamin D levels after 6 months of vitamin D replenishment with ergocalciferol
Time frame: 12 months
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