The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of recurrent implantation failure in IVF patient with cause unknown or due to thin endometrium. Several studies showed that GCSF improves embryo development and implantation and increase pregnancy rate.
The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of repeated implantation failure (5 cycles) in IVF patient with cause unknown or due to thin endometrium. we intend to treat with GCSF during the IVF cycle if thin endometrium (\<6 mm) is the cause for the treatment failure, and during the implantation window if cause unknown.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
20
neupogen 300 mcg - twice
Hadassah Ein Karem
Jerusalem, Israel, Israel
Hadassah Ein Karem
Jerusalem, Israel
pregnancy rate
Time frame: 18 months
endometrial thickness during IVF treatment
Time frame: 18 months
endometrial thickness
Time frame: 18 months
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