Effects of Xanthophylls on Optical Density

University of Jena20 enrolled

Overview

The objective of the study was to investigate the influence of a intervention with lutein und zeaxanthin from crucifers on the optical density of the macular pigment of patients with non exudative age-related maculopathy. It is hypothesized that the applied study beverage elevates plasma concentrations of the administered xanthophylls and the optical density after 4 weeks of intervention.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Age-Related Macular Degeneration

Interventions

VerumDIETARY_SUPPLEMENT

10 subjects consume for 4 weeks a beverage containing 10 mg lutein and 3 mg zeaxanthin per day

PlaceboDIETARY_SUPPLEMENT

10 subjects consume for 4 weeks a placebo beverage without any lutein and zeaxanthin

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * patients with non exudative age-related maculopathy Exclusion Criteria: * intake of dietary supplements containing lutein and zeaxanthin

Locations (1)

Friedrich Schiller University

Jena, Thuringia, Germany

Outcomes

Primary Outcomes

Optical density of macular pigment in AMD patients

Time frame: 10 weeks

Secondary Outcomes

Concentration of xanthophylls in plasma of AMD patients

Time frame: 10 weeks

blood lipids

Time frame: 10 weeks

Data from ClinicalTrials.gov

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